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human umbilical arterial endothelial cells huaecs  (PromoCell)


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    PromoCell human umbilical arterial endothelial cells huaecs
    Human Umbilical Arterial Endothelial Cells Huaecs, supplied by PromoCell, used in various techniques. Bioz Stars score: 95/100, based on 208 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+arterial+endothelial+cells+huaecs/Human+Umbilical+Artery+Endothelial+Cells/10__1096_slash_fj__202600061r-40-0-9
    Average 95 stars, based on 208 article reviews
    human umbilical arterial endothelial cells huaecs - by Bioz Stars, 2026-09
    95/100 stars

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    Cell Culture:

    Article Title: Interaction Between ALK1 Signaling and Connexin40 in the Development of Arteriovenous Malformations
    Article Snippet: .. Human Arterial Endothelial Cells (HuAECs) were obtained as described 7 and cultured in EGM-M2 SupplementPack (PromoCell, C-39211) at 37°C in 5% CO2. .. Cells were washed with phosphate-buffered saline (PBS) (Gibco, 14200-067) and then serum-starved for 5 hours prior to stimulation with either 1ng/ml for 3h or 10ng/ml BMP9 for 24h to assess the effect of BMP9 on gene expression.



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    Treatment with caspase-1 inhibitor decreased gene expression of ( A ) IL-1β, ( B ) GSDMD and protein expression of ( C ) IL-1β, ( D ) GSDMD in hyperoxia-exposed <t>endothelial</t> cells. ( E ) Representative western blots of IL-1β and of GSDMD in the endothelial cells. In addition, caspase-1 inhibitor also reduced gene expression of ( F ) IL-1β ( G ) GSDMD and protein expression of ( H ) IL-1β, ( I ) GSDMD in hyperoxia-exposed smooth muscle cells. ( J ) Representative western blots of IL-1β and of GSDMD in the smooth muscle cells. n = 4–5/group, data are mean ± SD, two-way ANOVA with Tukey’s multiple comparisons test. * P <0.05 ** P <0.01, *** P <0.001; **** P <0.0001. HYP, hyperoxia; PL, placebo; RA, room air; VX-765, caspase-1 Inhibitor.
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    Proposed pathway for the effects of COMP-4 in the human arterial <t>endothelial</t> cell.
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    Treatment with caspase-1 inhibitor decreased gene expression of ( A ) IL-1β, ( B ) GSDMD and protein expression of ( C ) IL-1β, ( D ) GSDMD in hyperoxia-exposed endothelial cells. ( E ) Representative western blots of IL-1β and of GSDMD in the endothelial cells. In addition, caspase-1 inhibitor also reduced gene expression of ( F ) IL-1β ( G ) GSDMD and protein expression of ( H ) IL-1β, ( I ) GSDMD in hyperoxia-exposed smooth muscle cells. ( J ) Representative western blots of IL-1β and of GSDMD in the smooth muscle cells. n = 4–5/group, data are mean ± SD, two-way ANOVA with Tukey’s multiple comparisons test. * P <0.05 ** P <0.01, *** P <0.001; **** P <0.0001. HYP, hyperoxia; PL, placebo; RA, room air; VX-765, caspase-1 Inhibitor.

    Journal: Clinical Science (London, England : 1979)

    Article Title: Caspase-1 inhibition mitigates neonatal hyperoxia-induced vascular and cardiopulmonary inflammation in neonatal rats

    doi: 10.1042/CS20242275

    Figure Lengend Snippet: Treatment with caspase-1 inhibitor decreased gene expression of ( A ) IL-1β, ( B ) GSDMD and protein expression of ( C ) IL-1β, ( D ) GSDMD in hyperoxia-exposed endothelial cells. ( E ) Representative western blots of IL-1β and of GSDMD in the endothelial cells. In addition, caspase-1 inhibitor also reduced gene expression of ( F ) IL-1β ( G ) GSDMD and protein expression of ( H ) IL-1β, ( I ) GSDMD in hyperoxia-exposed smooth muscle cells. ( J ) Representative western blots of IL-1β and of GSDMD in the smooth muscle cells. n = 4–5/group, data are mean ± SD, two-way ANOVA with Tukey’s multiple comparisons test. * P <0.05 ** P <0.01, *** P <0.001; **** P <0.0001. HYP, hyperoxia; PL, placebo; RA, room air; VX-765, caspase-1 Inhibitor.

    Article Snippet: Human Umbilical Artery Endothelial Cells, HUAECs (Cat# 202–05n, Cell Applications, San Diego, CA) were cultured in a human MesoEndo growth medium (Cat# 212–500, Cell Applications, San Diego, CA).

    Techniques: Gene Expression, Expressing, Western Blot

    Proposed pathway for the effects of COMP-4 in the human arterial endothelial cell.

    Journal: PLOS ONE

    Article Title: Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway

    doi: 10.1371/journal.pone.0316798

    Figure Lengend Snippet: Proposed pathway for the effects of COMP-4 in the human arterial endothelial cell.

    Article Snippet: Frozen human umbilical arterial endothelial cells (HUAEC, cat# 202-05n, Cell Applications, Inc., San Diego, CA) were thawed in a 37°C water bath.

    Techniques: